To summarize the nursing experience of a pregnant woman with primary mediastinal large B-cell lymphoma complicated with atmospheric tract stenosis. Nursing key points include inventory management to ensure the safety of ECMO two-way transport；setting up an exclusive nursing team to ensure the continuity of nursing process and effective implementation of decision-making；staged coagulation monitoring and management during ECMO and CRRT operation；doctor-nurse cooperation was carried out according to the patient’s condition to predict the related complications and formulate the process plan，to provide a safe guarantee for the prevention of airway obstruction，tumor lysis syndrome，catheter-related bloodstream infection and other related complications. At the same time，patients are provided with refined pregnancy management and individualized psychological intervention. The patient was hospitalized for 9 days. After careful treatment and nursing，the patient’s condition was and improved transferred to the department of obstetrics for further treatment.

The nursing experience of a patient with nephrotic syndrome complicated with pneumocystis and cytomegalovirus severe pneumonia was summarized. Nursing essentials include：nursing care of high flow vein - extracorporeal membrane oxygenation therapy with continuous renal replacement therapy of pressure monitoring;pipeline safety nursing of patients with the waking extracorporeal membrane oxygenation treatment,nursing care of continuous delirium condition;early recognition and treatment of blood coagulation dysfunction in the digestive tract hemorrhage,deep vein thrombosis prevention and nursing care;infection prevention and control of immunosuppressive state,nursing care of early lung rehabilitation and psychological intervention of patients. The patient was hospitalized for 51 days. After careful treatment and nursing,the patient gets better and was discharged.

The nursing experience of a patient with severe respiratory failure caused by 1,3-hexafluorobutadiene poisoning treated with high flow Extracorporeal Membrane Oxygenation（ECMO） for a long time was summarized. The key points of nursing include pneumothorax nursing,safety nursing of multiple hospital transfers under the support of high flow ECMO,nursing of multiple conversion mode and replacement of oxygenator under the support of high flow ECMO,nursing of bleeding and thrombotic complications and convulsions. The patient was treated with ECMO for 44 days. After careful treatment and nursing,the lung transplantation was successfully completed and ECMO was successfully removed. The condition improved and the patient was recovering.